| Name | What | Region | Country | Lat | Long | Elev ft. | Pop est |
|---|---|---|---|---|---|---|---|
| INGENIO SANTA ROSA | airport | Panama | 8.20 | -80.66 | 109 | 0 | |
| Ibala | city | Veraguas | Panama | 8.37 | -81.20 | 1669 | 7808 |
| Icacal | city | Colon | Panama | 9.13 | -80.38 | 314 | 521 |
| Icacal | city | Colon | Panama | 9.19 | -80.15 | 75 | 1951 |
| Icaco | city | Kuna Yala | Panama | 9.57 | -78.83 | 0 | 25 |
| Icaco | city | Colon | Panama | 9.13 | -80.38 | 314 | 521 |
| Icanti | city | Panama | Panama | 9.21 | -78.68 | 144 | 0 |
| Icotupo | city | Kuna Yala | Panama | 9.50 | -78.95 | 0 | 73 |
| Iguanita | city | Colon | Panama | 9.50 | -79.68 | 150 | 2019 |
| India Vieja | city | Chiriqui | Panama | 8.75 | -82.35 | 4189 | 3129 |
| Infiernillo | city | Veraguas | Panama | 7.28 | -80.92 | 173 | 214 |
| Infiernillo | city | Los Santos | Panama | 7.45 | -80.30 | 157 | 989 |
| Ingenio La Estrella | city | Cocle | Panama | 8.28 | -80.52 | 22 | 12777 |
| Ingenio Santa Rosa | city | Cocle | Panama | 8.20 | -80.67 | 78 | 13846 |
| Ingenio de Santa Rosa | city | Cocle | Panama | 8.20 | -80.67 | 78 | 13846 |
| Ingenio de la Estrella | city | Cocle | Panama | 8.28 | -80.52 | 22 | 12777 |
| Ipeti | city | Panama | Panama | 8.97 | -78.50 | 1669 | 0 |
| Ipeti Colono | city | Panama | Panama | 8.98 | -78.52 | 1197 | 0 |
| Ipetí Chocó | city | Panama | Panama | 8.97 | -78.53 | 1154 | 0 |
| Iquinina | city | Darien | Panama | 8.84 | -77.98 | 177 | 375 |
| Irgandí | city | Kuna Yala | Panama | 9.33 | -78.31 | 3 | 685 |
| Isabel Sanchez | city | Panama Oeste | Panama | 8.88 | -79.98 | 862 | 5456 |
| Isla | city | Kuna Yala | Panama | 9.59 | -78.89 | 0 | 24 |
| Isla Aguja | city | Kuna Yala | Panama | 9.50 | -78.95 | 0 | 73 |
| Isla Carenero | city | Bocas del Toro | Panama | 9.34 | -82.23 | 0 | 2318 |
| Isla Cartí Tupile | city | Kuna Yala | Panama | 9.47 | -78.96 | 0 | 484 |
| Isla Cuba | city | Kuna Yala | Panama | 8.92 | -77.72 | 0 | 546 |
| Isla Gallinazo | city | Kuna Yala | Panama | 8.94 | -77.75 | 3 | 982 |
| Isla Grande | city | Colon | Panama | 9.63 | -79.57 | 72 | 1008 |
| Isla Grande | city | Bocas del Toro | Panama | 9.48 | -82.67 | 82 | 1043 |
| Isla La Canas | city | Los Santos | Panama | 7.41 | -80.32 | 0 | 586 |
| Isla Linton | city | Colon | Panama | 9.62 | -79.58 | 118 | 1332 |
| Isla Mamey | city | Panama | Panama | 8.43 | -78.86 | 3 | 349 |
| Isla Pino | city | Kuna Yala | Panama | 9.00 | -77.76 | 0 | 585 |
| Isla Popa Número Dos | city | Bocas del Toro | Panama | 9.22 | -82.14 | 16 | 457 |
| Isla Ratón | city | Kuna Yala | Panama | 9.44 | -78.84 | 3 | 622 |
| Isla Tigre | city | Kuna Yala | Panama | 9.43 | -78.52 | 0 | 1521 |
| Isla Tigre | city | Bocas del Toro | Panama | 9.17 | -82.08 | 0 | 471 |
| Isla Torta | city | Chiriqui | Panama | 8.23 | -82.30 | 0 | 1494 |
| Isla Venado | city | Bocas del Toro | Panama | 9.32 | -82.55 | 344 | 1043 |
| Isla Wichitupo Grande | city | Kuna Yala | Panama | 9.59 | -78.89 | 0 | 24 |
| Isla de Canas | city | Los Santos | Panama | 7.41 | -80.32 | 0 | 586 |
| Isla de Cedro | city | Chiriqui | Panama | 8.23 | -82.23 | 3 | 714 |
| Isla de Pato | city | Panama | Panama | 9.22 | -78.93 | 98 | 0 |
| Isla de Patos | city | Panama | Panama | 9.22 | -78.93 | 98 | 0 |
| Isla de Pino | city | Kuna Yala | Panama | 9.00 | -77.76 | 0 | 585 |
| Isleta | city | Panama Oeste | Panama | 8.92 | -79.72 | 39 | 136542 |
| Isleta | city | Darien | Panama | 8.63 | -78.15 | 6 | 435 |
| Istmito | city | Bocas del Toro | Panama | 9.35 | -82.25 | 3 | 2404 |