| Name | What | Region | Country | Lat | Long | Elev ft. | Pop est |
|---|---|---|---|---|---|---|---|
| Sabie River | city | Nova Scotia | Canada | 43.84 | -65.06 | 3 | 144 |
| Sable River | city | Nova Scotia | Canada | 43.84 | -65.06 | 3 | 144 |
| Saint Ann | city | Nova Scotia | Canada | 46.25 | -60.62 | 187 | 26 |
| Saint Anns | city | Nova Scotia | Canada | 46.25 | -60.62 | 187 | 26 |
| Saint Francis Harbour | city | Nova Scotia | Canada | 45.47 | -61.26 | 6 | 128 |
| Saint Peters | city | Nova Scotia | Canada | 45.69 | -60.84 | 3 | 386 |
| Saint-Joseph-du-Moine | city | Nova Scotia | Canada | 46.55 | -61.08 | 0 | 36 |
| Salmon River | city | Nova Scotia | Canada | 44.05 | -66.17 | 6 | 496 |
| Sambro | city | Nova Scotia | Canada | 44.45 | -63.57 | 0 | 218 |
| Sandford | city | Nova Scotia | Canada | 43.92 | -66.15 | 101 | 1146 |
| Sandy Point | city | Nova Scotia | Canada | 43.71 | -65.32 | 98 | 1632 |
| Saulnierville | city | Nova Scotia | Canada | 44.23 | -66.17 | 0 | 223 |
| Saulnierville Station | city | Nova Scotia | Canada | 44.23 | -66.17 | 0 | 223 |
| Scots Bay | city | Nova Scotia | Canada | 45.25 | -64.39 | 830 | 1303 |
| Scotsburn | city | Nova Scotia | Canada | 45.65 | -62.85 | 252 | 1804 |
| Scotsville | city | Nova Scotia | Canada | 46.21 | -61.16 | 196 | 298 |
| Seafoam | city | Nova Scotia | Canada | 45.79 | -63.00 | 39 | 149 |
| Seaforth | city | Nova Scotia | Canada | 44.65 | -63.27 | 0 | 1584 |
| Seaview | city | Nova Scotia | Canada | 45.71 | -60.94 | 206 | 447 |
| Selma | city | Nova Scotia | Canada | 45.29 | -63.51 | 98 | 0 |
| Shag Harbor | city | Nova Scotia | Canada | 43.50 | -65.70 | 3 | 497 |
| Sheet Harbour | city | Nova Scotia | Canada | 44.91 | -62.48 | 118 | 141 |
| Shelburne | city | Nova Scotia | Canada | 43.75 | -65.25 | 134 | 964 |
| Shelburne Harbour | city | Nova Scotia | Canada | 43.75 | -65.25 | 134 | 964 |
| Shenacadie | city | Nova Scotia | Canada | 46.02 | -60.65 | 830 | 1653 |
| Shenacadle | city | Nova Scotia | Canada | 46.02 | -60.65 | 830 | 1653 |
| Sherbrooke | city | Nova Scotia | Canada | 45.13 | -61.98 | 19 | 133 |
| Ship Harbour | city | Nova Scotia | Canada | 44.79 | -62.83 | 3 | 0 |
| Shubenacadie | city | Nova Scotia | Canada | 45.05 | -63.38 | 75 | 4392 |
| Shunacadie | city | Nova Scotia | Canada | 46.02 | -60.65 | 830 | 1653 |
| Sidney | city | Nova Scotia | Canada | 46.15 | -60.17 | 118 | 6081 |
| Sidney Mines | city | Nova Scotia | Canada | 46.23 | -60.22 | 0 | 4474 |
| Sidni-a-Tuath | city | Nova Scotia | Canada | 46.20 | -60.25 | 0 | 5511 |
| Sluice Point | city | Nova Scotia | Canada | 43.79 | -65.96 | 22 | 1234 |
| Smith's | city | Nova Scotia | Canada | 46.02 | -61.52 | 229 | 391 |
| Smith’s | city | Nova Scotia | Canada | 46.02 | -61.52 | 229 | 391 |
| Soldier Cove | city | Nova Scotia | Canada | 45.70 | -60.73 | 144 | 584 |
| Soldiers Cove | city | Nova Scotia | Canada | 45.70 | -60.73 | 144 | 584 |
| Sommerville Center | city | Nova Scotia | Canada | 43.96 | -64.82 | 3 | 106 |
| Sonora | city | Nova Scotia | Canada | 45.07 | -61.84 | 0 | 49 |
| South Alton | city | Nova Scotia | Canada | 44.98 | -64.53 | 830 | 2432 |
| South Brookfield | city | Nova Scotia | Canada | 44.37 | -64.97 | 285 | 307 |
| South Joggings | city | Nova Scotia | Canada | 45.69 | -64.44 | 200 | 90 |
| South Joggins | city | Nova Scotia | Canada | 45.69 | -64.44 | 200 | 90 |
| South Lochaber | city | Nova Scotia | Canada | 45.38 | -62.00 | 298 | 305 |
| South Maitland | city | Nova Scotia | Canada | 45.22 | -63.45 | 196 | 0 |
| South Maitland | city | Nova Scotia | Canada | 45.28 | -63.48 | 98 | 0 |
| South Merland | city | Nova Scotia | Canada | 45.55 | -61.60 | 272 | 572 |
| South Milford | city | Nova Scotia | Canada | 44.53 | -65.42 | 830 | 0 |
| South West Margaree | city | Nova Scotia | Canada | 46.30 | -61.15 | 173 | 298 |
| South West Port Mouton | city | Nova Scotia | Canada | 43.90 | -64.81 | 13 | 79 |
| Southside Antigonish Harbour | city | Nova Scotia | Canada | 45.66 | -61.86 | 98 | 766 |
| Southville | city | Nova Scotia | Canada | 44.31 | -65.92 | 288 | 877 |
| Spencer Island | city | Nova Scotia | Canada | 45.31 | -64.71 | 0 | 50 |
| Spencers Island | city | Nova Scotia | Canada | 45.31 | -64.71 | 0 | 50 |
| Springfield | city | Nova Scotia | Canada | 44.59 | -64.86 | 830 | 624 |
| Springhill | city | Nova Scotia | Canada | 45.65 | -64.06 | 830 | 5778 |
| Springhill Junction | city | Nova Scotia | Canada | 45.69 | -64.10 | 236 | 1676 |
| Springville | city | Nova Scotia | Canada | 45.45 | -62.63 | 196 | 743 |
| Stellarton | city | Nova Scotia | Canada | 45.57 | -62.65 | 65 | 20500 |
| Stewiacke | city | Nova Scotia | Canada | 45.13 | -63.35 | 104 | 3563 |
| Stewiacke East | city | Nova Scotia | Canada | 45.11 | -63.27 | 173 | 396 |
| Stony Island | city | Nova Scotia | Canada | 43.47 | -65.57 | 3 | 422 |
| Stormont | city | Nova Scotia | Canada | 45.22 | -61.73 | 3 | 241 |
| Strathlorne | city | Nova Scotia | Canada | 46.18 | -61.27 | 187 | 1286 |
| Street Ridge | city | Nova Scotia | Canada | 45.72 | -63.64 | 150 | 298 |
| Summerville Centre | city | Nova Scotia | Canada | 43.96 | -64.82 | 3 | 106 |
| Sunnybrae | city | Nova Scotia | Canada | 45.40 | -62.50 | 298 | 0 |
| Surettes Island | city | Nova Scotia | Canada | 43.77 | -65.93 | 3 | 614 |
| Swansburg | city | Nova Scotia | Canada | 43.72 | -65.03 | 9 | 59 |
| Sydney | city | Nova Scotia | Canada | 46.15 | -60.17 | 118 | 6081 |
| Sydney Mines | city | Nova Scotia | Canada | 46.23 | -60.22 | 0 | 4474 |
| Sydney River | city | Nova Scotia | Canada | 46.12 | -60.22 | 160 | 6081 |