| Name | What | Region | Country | Lat | Long | Elev ft. | Pop est |
|---|---|---|---|---|---|---|---|
| Espanita Forest | city | Louisiana | United States | 32.55 | -93.61 | 196 | |
| Espanita Village | city | Louisiana | United States | 32.55 | -93.61 | 196 | |
| Espanola | city | Florida | United States | 29.51 | -81.31 | 22 | |
| Espanola | city | Washington | United States | 47.60 | -117.74 | 2509 | |
| Espanta Sueño | city | Puerto Rico | United States | 18.32 | -65.66 | 16 | |
| Espantosa Colonia | city | Texas | United States | 28.63 | -99.83 | 830 | |
| Esparto | city | California | United States | 38.69 | -122.02 | 177 | |
| Esparza Colonia Number 1 | city | Texas | United States | 26.03 | -97.63 | 36 | |
| Esparza Colonia Number 2 | city | Texas | United States | 26.03 | -97.63 | 36 | |
| Española | city | New Mexico | United States | 35.99 | -106.08 | 5869 | |
| Espelie | city | Minnesota | United States | 48.22 | -95.68 | 1167 | |
| Espenberg | city | Alaska | United States | 66.59 | -163.96 | 6 | |
| Esper | city | Missouri | United States | 40.53 | -92.85 | 948 | |
| Esperance | city | New York | United States | 42.76 | -74.26 | 830 | |
| Esperance | city | Washington | United States | 47.79 | -122.36 | 400 | |
| Esperance Landing | city | Louisiana | United States | 31.40 | -91.48 | 19 | |
| Esperanza | city | Mississippi | United States | 34.36 | -89.16 | 377 | |
| Esperanza | city | Texas | United States | 31.16 | -105.71 | 3497 | |
| Esperanza | city | Texas | United States | 30.49 | -95.49 | 347 | |
| Esperanza | city | Puerto Rico | United States | 17.96 | -66.26 | 26 | |
| Esperanza | city | Puerto Rico | United States | 17.99 | -66.57 | 9 | |
| Esperanza | city | Puerto Rico | United States | 18.21 | -66.07 | 830 | |
| Esperanza | city | Puerto Rico | United States | 18.22 | -65.69 | 62 | |
| Esperanza | city | Puerto Rico | United States | 18.10 | -65.47 | 13 | |
| Esperanza | city | California | United States | 33.88 | -117.76 | 396 | |
| Esperanza (historical) | city | California | United States | 41.26 | -122.05 | 3402 | |
| Esperanza Comunidad | city | Puerto Rico | United States | 18.10 | -65.48 | 0 | |
| Esperanza Estates Colonia | city | Texas | United States | 26.16 | -98.11 | 82 | |
| Esperanza Farm | city | Maryland | United States | 38.30 | -76.47 | 42 | |
| Esperson | city | Texas | United States | 29.96 | -94.92 | 52 | |
| Espey | city | Texas | United States | 29.11 | -98.49 | 830 | |
| Espino | city | Puerto Rico | United States | 18.28 | -67.12 | 124 | |
| Espino Comunidad | city | Puerto Rico | United States | 18.28 | -67.12 | 124 | |
| Espinosa | city | Colorado | United States | 37.13 | -105.95 | 7775 | |
| Espinosa | city | Puerto Rico | United States | 18.42 | -66.32 | 196 | |
| Esplanada | city | Arizona | United States | 33.35 | -111.85 | 1256 | |
| Esplanade Gardens | city | New York | United States | 40.82 | -73.94 | 16 | |
| Esplen | city | Pennsylvania | United States | 40.46 | -80.05 | 830 | |
| Espuela | city | New Mexico | United States | 32.93 | -104.39 | 3379 | |
| Espy | city | Pennsylvania | United States | 41.01 | -76.41 | 830 | |
| Espyville | city | Ohio | United States | 40.60 | -83.26 | 912 | |
| Espyville | city | Pennsylvania | United States | 41.61 | -80.49 | 1053 |