| Name | What | Region | Country | Lat | Long | Elev ft. | Pop est |
|---|---|---|---|---|---|---|---|
| Wide Awake | city | South Carolina | United States | 33.05 | -80.11 | 55 | |
| Wiggins | city | South Carolina | United States | 32.60 | -80.54 | 3 | |
| Wilburn (historical) | city | South Carolina | United States | 35.10 | -81.46 | 830 | |
| Wildaire | city | South Carolina | United States | 34.88 | -82.35 | 912 | |
| Wildcat (historical) | city | South Carolina | United States | 34.64 | -81.83 | 830 | |
| Wilder | city | South Carolina | United States | 33.35 | -79.94 | 49 | |
| Wilder (historical) | city | South Carolina | United States | 33.35 | -79.94 | 49 | |
| Wildewood | city | South Carolina | United States | 34.10 | -80.88 | 344 | |
| Wildwood | city | South Carolina | United States | 32.91 | -80.04 | 29 | |
| Wildwood Park (historical) | city | South Carolina | United States | 35.15 | -82.41 | 1230 | |
| Wiles Crossroads | city | South Carolina | United States | 33.71 | -80.67 | 252 | |
| Wilkes Crossroads | city | South Carolina | United States | 34.21 | -80.04 | 164 | |
| Wilkins | city | South Carolina | United States | 32.48 | -80.60 | 6 | |
| Wilkinson Heights | city | South Carolina | United States | 33.50 | -80.83 | 200 | |
| Wilkinsville | city | South Carolina | United States | 34.97 | -81.53 | 830 | |
| Wilksburg | city | South Carolina | United States | 34.75 | -81.39 | 830 | |
| Williams | city | South Carolina | United States | 33.03 | -80.84 | 98 | |
| Williams Estates | city | South Carolina | United States | 34.33 | -79.89 | 150 | |
| Williams Heights | city | South Carolina | United States | 34.22 | -79.77 | 124 | |
| Williams Hill | city | South Carolina | United States | 33.72 | -79.32 | 49 | |
| Williams Plaza | city | South Carolina | United States | 33.50 | -80.81 | 196 | |
| Williamsburg East | city | South Carolina | United States | 34.07 | -80.90 | 262 | |
| Williamsburg Estates | city | South Carolina | United States | 34.93 | -81.87 | 830 | |
| Williamsburg Manor | city | South Carolina | United States | 34.51 | -82.63 | 830 | |
| Williamston | city | South Carolina | United States | 34.62 | -82.48 | 830 | |
| Willie Towne | city | South Carolina | United States | 33.54 | -79.43 | 26 | |
| Willington | city | South Carolina | United States | 33.97 | -82.47 | 830 | |
| Willington Green | city | South Carolina | United States | 34.88 | -82.33 | 948 | |
| Williston | city | South Carolina | United States | 33.40 | -81.42 | 341 | |
| Willow Acres | city | South Carolina | United States | 34.99 | -81.09 | 830 | |
| Willow Creek Siding | city | South Carolina | United States | 34.09 | -79.65 | 78 | |
| Willow Heights | city | South Carolina | United States | 34.90 | -82.36 | 1046 | |
| Willow Springs Park | city | South Carolina | United States | 33.52 | -81.91 | 200 | |
| Willow Wood | city | South Carolina | United States | 35.01 | -82.02 | 866 | |
| Willowbrook | city | South Carolina | United States | 32.99 | -80.01 | 26 | |
| Willtown (historical) | city | South Carolina | United States | 33.62 | -79.45 | 26 | |
| Willtown Bluff | city | South Carolina | United States | 32.68 | -80.41 | 29 | |
| Wilson | city | South Carolina | United States | 33.66 | -80.12 | 108 | |
| Wilson Crossroads | city | South Carolina | United States | 33.80 | -80.12 | 95 | |
| Wilson Crossroads | city | South Carolina | United States | 34.22 | -79.90 | 157 | |
| Wilson Estates | city | South Carolina | United States | 34.22 | -79.76 | 127 | |
| Wilson Heights | city | South Carolina | United States | 34.21 | -79.76 | 127 | |
| Wilson Landing | city | South Carolina | United States | 33.83 | -79.00 | 19 | |
| Wilsons Landing | city | South Carolina | United States | 33.45 | -80.16 | 52 | |
| Wilsonville | city | South Carolina | United States | 32.91 | -80.04 | 29 | |
| Windhams Crossroads | city | South Carolina | United States | 34.20 | -80.03 | 160 | |
| Windjammer Village | city | South Carolina | United States | 33.58 | -79.01 | 6 | |
| Windmill Harbor | city | South Carolina | United States | 32.22 | -80.78 | 3 | |
| Windom Corner | city | South Carolina | United States | 33.13 | -79.71 | 29 | |
| Windsor | city | South Carolina | United States | 33.48 | -81.51 | 390 | |
| Windsor City Mobile Home Park | city | South Carolina | United States | 33.97 | -80.40 | 180 | |
| Windsor Estates | city | South Carolina | United States | 34.08 | -80.93 | 262 | |
| Windsor Forest | city | South Carolina | United States | 34.90 | -81.89 | 830 | |
| Windsor Forest | city | South Carolina | United States | 34.20 | -79.82 | 118 | |
| Windsor Heights | city | South Carolina | United States | 34.27 | -80.64 | 226 | |
| Windsor Lake Park | city | South Carolina | United States | 34.07 | -80.94 | 285 | |
| Windsor Oaks | city | South Carolina | United States | 34.90 | -82.30 | 931 | |
| Windsor Park | city | South Carolina | United States | 34.70 | -79.92 | 154 | |
| Windsor Place | city | South Carolina | United States | 32.84 | -79.96 | 6 | |
| Windsor Place | city | South Carolina | United States | 34.53 | -82.63 | 830 | |
| Windtree | city | South Carolina | United States | 33.57 | -81.95 | 830 | |
| Windtree | city | South Carolina | United States | 34.24 | -82.16 | 830 | |
| Windward Trail | city | South Carolina | United States | 34.60 | -82.61 | 830 | |
| Windwood | city | South Carolina | United States | 33.11 | -80.08 | 75 | |
| Windy Hills | city | South Carolina | United States | 33.52 | -80.87 | 252 | |
| Wineberg Crossroads | city | South Carolina | United States | 34.28 | -79.98 | 190 | |
| Wing Road | city | South Carolina | United States | 33.42 | -80.07 | 78 | |
| Winnsboro | city | South Carolina | United States | 34.38 | -81.09 | 830 | |
| Winnsboro Mills | city | South Carolina | United States | 34.36 | -81.09 | 830 | |
| Winona | city | South Carolina | United States | 34.21 | -79.60 | 91 | |
| Winona | city | South Carolina | United States | 34.37 | -82.38 | 830 | |
| Winter Park | city | South Carolina | United States | 33.92 | -80.41 | 180 | |
| Wintercrest | city | South Carolina | United States | 34.96 | -81.07 | 830 | |
| Winterseat | city | South Carolina | United States | 33.98 | -82.20 | 830 | |
| Winthrop Heights | city | South Carolina | United States | 34.95 | -81.00 | 830 | |
| Winwright (historical) | city | South Carolina | United States | 32.88 | -80.29 | 29 | |
| Wisacky | city | South Carolina | United States | 34.15 | -80.19 | 183 | |
| Wise (historical) | city | South Carolina | United States | 33.69 | -81.92 | 830 | |
| Wisewood | city | South Carolina | United States | 34.15 | -82.14 | 830 | |
| Witherbee | city | South Carolina | United States | 33.16 | -79.83 | 36 | |
| Withers Heights | city | South Carolina | United States | 33.68 | -78.90 | 0 |