| Name | What | Region | Country | Lat | Long | Elev ft. | Pop est |
|---|---|---|---|---|---|---|---|
| Black | city | South Carolina | United States | 34.34 | -82.29 | 830 | |
| Black Creek | city | South Carolina | United States | 33.28 | -80.26 | 88 | |
| Black Gate | city | South Carolina | United States | 34.25 | -81.99 | 830 | |
| Black Horse Run | city | South Carolina | United States | 35.00 | -80.85 | 830 | |
| Black Jack Valley (historical) | city | South Carolina | United States | 34.69 | -81.80 | 830 | |
| Black Tom (historical) | city | South Carolina | United States | 33.13 | -80.15 | 59 | |
| Blacks | city | South Carolina | United States | 33.92 | -81.68 | 830 | |
| Blacksburg | city | South Carolina | United States | 35.12 | -81.52 | 830 | |
| Blackstock | city | South Carolina | United States | 34.56 | -81.15 | 830 | |
| Blackville | city | South Carolina | United States | 33.36 | -81.27 | 288 | |
| Bladen | city | South Carolina | United States | 34.34 | -80.08 | 209 | |
| Blair | city | South Carolina | United States | 34.42 | -81.40 | 318 | |
| Blairsville | city | South Carolina | United States | 34.92 | -81.35 | 830 | |
| Blake | city | South Carolina | United States | 32.69 | -80.77 | 13 | |
| Blakedale | city | South Carolina | United States | 34.22 | -82.19 | 830 | |
| Blakely | city | South Carolina | United States | 33.49 | -79.76 | 59 | |
| Blakley Crossroads | city | South Carolina | United States | 34.58 | -80.85 | 830 | |
| Blaney Hills | city | South Carolina | United States | 34.17 | -80.77 | 301 | |
| Blaney West | city | South Carolina | United States | 34.17 | -80.81 | 305 | |
| Bleases Crossroads | city | South Carolina | United States | 34.06 | -81.81 | 830 | |
| Blenheim | city | South Carolina | United States | 34.51 | -79.65 | 88 | |
| Bloomingvale | city | South Carolina | United States | 33.55 | -79.61 | 39 | |
| Bloomville | city | South Carolina | United States | 33.63 | -80.16 | 111 | |
| Blossom | city | South Carolina | United States | 33.95 | -79.57 | 72 | |
| Blountville | city | South Carolina | United States | 32.70 | -80.85 | 22 | |
| Blue Brick | city | South Carolina | United States | 34.22 | -79.52 | 49 | |
| Blue Heaven | city | South Carolina | United States | 34.41 | -82.27 | 830 | |
| Blue Heron | city | South Carolina | United States | 33.54 | -79.06 | 6 | |
| Blue Heron Bluff | city | South Carolina | United States | 32.44 | -80.65 | 19 | |
| Blue Ridge | city | South Carolina | United States | 35.04 | -82.31 | 1013 | |
| Blue Ridge Terrace | city | South Carolina | United States | 33.89 | -81.17 | 364 | |
| Blue Spring (historical) | city | South Carolina | United States | 34.42 | -80.33 | 246 | |
| Bluehouse Corners | city | South Carolina | United States | 32.77 | -80.70 | 29 | |
| Bluff Estates | city | South Carolina | United States | 33.94 | -80.97 | 147 | |
| Bluff Farm | city | South Carolina | United States | 32.44 | -80.64 | 19 | |
| Bluffton | city | South Carolina | United States | 32.24 | -80.86 | 19 | |
| Blynn Acres | city | South Carolina | United States | 33.74 | -78.84 | 19 | |
| Blythewood | city | South Carolina | United States | 34.21 | -80.97 | 830 |