| Name | What | Region | Country | Lat | Long | Elev ft. | Pop est |
|---|---|---|---|---|---|---|---|
| Daguao | city | Puerto Rico | United States | 18.23 | -65.68 | 45 | |
| Daguao Comunidad | city | Puerto Rico | United States | 18.22 | -65.68 | 45 | |
| Daguey | city | Puerto Rico | United States | 18.29 | -67.14 | 98 | |
| Daney | city | Puerto Rico | United States | 18.37 | -66.02 | 236 | |
| Davila | city | Puerto Rico | United States | 18.40 | -66.18 | 111 | |
| Davita y Llenza | city | Puerto Rico | United States | 18.42 | -66.05 | 22 | |
| De Diego | city | Puerto Rico | United States | 18.38 | -66.07 | 141 | |
| Del Carmen | city | Puerto Rico | United States | 18.40 | -66.04 | 104 | |
| Del Carmen | city | Puerto Rico | United States | 18.47 | -66.85 | 298 | |
| Del Carmen | city | Puerto Rico | United States | 18.47 | -66.94 | 400 | |
| Delicias | city | Puerto Rico | United States | 18.10 | -67.16 | 36 | |
| Delicias | city | Puerto Rico | United States | 18.40 | -66.05 | 127 | |
| Descalabrado | city | Puerto Rico | United States | 18.01 | -66.43 | 88 | |
| Destino | city | Puerto Rico | United States | 18.13 | -65.44 | 85 | |
| Desvío Dolores | city | Puerto Rico | United States | 18.38 | -65.86 | 39 | |
| Divisoria | city | Puerto Rico | United States | 18.16 | -66.51 | 2024 | |
| Dolores Gonzales Diaz Don Lolo | city | Puerto Rico | United States | 18.19 | -65.96 | 354 | |
| Domencech | city | Puerto Rico | United States | 18.49 | -67.03 | 259 | |
| Domingo Ortiz | city | Puerto Rico | United States | 18.20 | -67.15 | 52 | |
| Domingo Ruíz | city | Puerto Rico | United States | 18.45 | -66.68 | 91 | |
| Dominguito | city | Puerto Rico | United States | 18.42 | -66.75 | 830 | |
| Dona Clara | city | Puerto Rico | United States | 17.98 | -66.91 | 269 | |
| Dorado | city | Puerto Rico | United States | 18.46 | -66.27 | 13 | |
| Dorado Zona Urbana | city | Puerto Rico | United States | 18.47 | -66.27 | 26 | |
| Dorado del Mar | city | Puerto Rico | United States | 18.47 | -66.28 | 16 | |
| Doraville | city | Puerto Rico | United States | 18.44 | -66.28 | 55 | |
| Dos Bocas | city | Puerto Rico | United States | 18.34 | -66.67 | 898 | |
| Dos Pinos | city | Puerto Rico | United States | 18.40 | -66.04 | 68 | |
| Dos Rios | city | Puerto Rico | United States | 18.43 | -66.17 | 13 | |
| Dos Rios | city | Puerto Rico | United States | 18.35 | -66.47 | 403 | |
| Duque | city | Puerto Rico | United States | 18.24 | -65.75 | 282 | |
| Duque Comunidad | city | Puerto Rico | United States | 18.24 | -65.74 | 354 |