| Name | What | Region | Country | Lat | Long | Elev ft. | Pop est |
|---|---|---|---|---|---|---|---|
| Frailie | city | Missouri | United States | 36.42 | -89.82 | 269 | |
| Frankclay | city | Missouri | United States | 37.86 | -90.62 | 830 | |
| Frankenstein | city | Missouri | United States | 38.57 | -91.88 | 830 | |
| Frankford | city | Missouri | United States | 39.49 | -91.32 | 830 | |
| Franklin | city | Missouri | United States | 39.01 | -92.75 | 830 | |
| Franklin County Country Club | city | Missouri | United States | 38.50 | -91.04 | 830 | |
| Franks | city | Missouri | United States | 37.95 | -92.04 | 898 | |
| Frankville | city | Missouri | United States | 36.70 | -91.81 | 921 | |
| Frazier | city | Missouri | United States | 39.63 | -94.67 | 925 | |
| Fredericksburg | city | Missouri | United States | 38.61 | -91.64 | 830 | |
| Fredericktown | city | Missouri | United States | 37.56 | -90.29 | 830 | |
| Fredericktown Country Club | city | Missouri | United States | 37.55 | -90.33 | 830 | |
| Fredericktown District Ranger Station | city | Missouri | United States | 37.57 | -90.28 | 830 | |
| Fredville | city | Missouri | United States | 36.91 | -94.41 | 1141 | |
| Freeburg | city | Missouri | United States | 38.32 | -91.92 | 830 | |
| Freedom | city | Missouri | United States | 38.46 | -91.69 | 830 | |
| Freedom | city | Missouri | United States | 38.04 | -92.59 | 830 | |
| Freedom Community Center | city | Missouri | United States | 37.03 | -94.24 | 1148 | |
| Freeman | city | Missouri | United States | 38.62 | -94.51 | 853 | |
| Freeman | city | Missouri | United States | 37.14 | -90.92 | 830 | |
| Freeman Park (historical) | city | Missouri | United States | 39.77 | -94.64 | 862 | |
| Freeman Wastewater Treatment Facility | city | Missouri | United States | 38.62 | -94.49 | 830 | |
| Freemans Store | city | Missouri | United States | 37.65 | -91.87 | 1200 | |
| Freistatt | city | Missouri | United States | 37.02 | -93.90 | 1669 | |
| Fremont | city | Missouri | United States | 36.95 | -91.16 | 830 | |
| Fremont Center | city | Missouri | United States | 37.16 | -93.27 | 1669 | |
| Fremont Hills | city | Missouri | United States | 37.07 | -93.25 | 1669 | |
| Fremont Picnic Area | city | Missouri | United States | 36.97 | -91.22 | 902 | |
| Fremont Tower Picnic Area | city | Missouri | United States | 36.96 | -91.22 | 902 | |
| French Mills | city | Missouri | United States | 37.46 | -90.49 | 830 | |
| French Town | city | Missouri | United States | 37.96 | -90.67 | 892 | |
| French Village | city | Missouri | United States | 37.97 | -90.39 | 898 | |
| French Village (historical) | city | Missouri | United States | 38.58 | -91.97 | 830 | |
| Frey Ford | city | Missouri | United States | 36.59 | -91.27 | 830 | |
| Friedenberg | city | Missouri | United States | 37.70 | -89.79 | 830 | |
| Friedheim | city | Missouri | United States | 37.57 | -89.82 | 830 | |
| Friedheim Station | city | Missouri | United States | 37.55 | -89.83 | 830 | |
| Friendly Valley | city | Missouri | United States | 37.69 | -89.91 | 830 | |
| Friendship Community Hall | city | Missouri | United States | 37.66 | -93.74 | 958 | |
| Friendship School | city | Missouri | United States | 37.82 | -92.63 | 1095 | |
| Frisbee | city | Missouri | United States | 36.35 | -90.03 | 262 | |
| Frisco | city | Missouri | United States | 36.76 | -89.86 | 295 | |
| Frisco School (historical) | city | Missouri | United States | 36.74 | -89.86 | 288 | |
| Frisco School (historical) | city | Missouri | United States | 36.76 | -89.86 | 295 | |
| Fristoe | city | Missouri | United States | 38.12 | -93.28 | 994 | |
| Froemsdorf | city | Missouri | United States | 37.22 | -89.49 | 400 | |
| Frogtown | city | Missouri | United States | 37.98 | -90.77 | 1033 | |
| Frohna | city | Missouri | United States | 37.64 | -89.62 | 830 | |
| Frontenac | city | Missouri | United States | 38.64 | -90.42 | 830 | |
| Frostwood Shopping Center | city | Missouri | United States | 38.76 | -90.33 | 830 | |
| Fruit City | city | Missouri | United States | 37.29 | -91.04 | 997 | |
| Fruitland | city | Missouri | United States | 37.45 | -89.64 | 830 | |
| Fruitland | city | Missouri | United States | 37.39 | -93.23 | 1256 | |
| Fruitville | city | Missouri | United States | 36.62 | -91.77 | 898 | |
| Frumet | city | Missouri | United States | 38.16 | -90.69 | 830 | |
| Fry School (historical) | city | Missouri | United States | 39.43 | -94.60 | 984 |