| Name | What | Region | Country | Lat | Long | Elev Ft. | Pop Est |
|---|
| Saddlestring | city | Wyoming | United States | 44.455 | -106.89667 | 5488 | 19 |
| Sage | city | Wyoming | United States | 41.81361 | -110.9575 | 6368 | 28 |
| Saint Stephens | city | Wyoming | United States | 42.98389 | -108.41583 | 4999 | 5589 |
| Sales Place | city | Wyoming | United States | 44.19 | -108.53556 | 4780 | 61 |
| Salt Creek historical | city | Wyoming | United States | 43.34889 | -106.32528 | 4904 | 166 |
| Salt Wells | city | Wyoming | United States | 41.65472 | -108.98528 | 6361 | 7 |
| Sampo historical | city | Wyoming | United States | 41.90194 | -106.49194 | 6998 | 47 |
| Sand Creek Crossing | city | Wyoming | United States | 44.41389 | -104.09556 | 5629 | 238 |
| Sand Draw | city | Wyoming | United States | 42.76056 | -108.18083 | 5994 | 5 |
| Saratoga | city | Wyoming | United States | 41.455 | -106.80583 | 6797 | 134 |
| Savageton | city | Wyoming | United States | 43.86583 | -105.78694 | 5059 | 56 |
| Savery | city | Wyoming | United States | 41.025 | -107.44917 | 6597 | 38 |
| Seely | city | Wyoming | United States | 44.80778 | -104.62 | 4146 | 47 |
| Seminoe Dam | city | Wyoming | United States | 42.15667 | -106.91333 | 6801 | 18 |
| Shawnee | city | Wyoming | United States | 42.74778 | -105.00917 | 5022 | 56 |
| Shell | city | Wyoming | United States | 44.53556 | -107.77917 | 4337 | 99 |
| Sheridan | city | Wyoming | United States | 44.79722 | -106.95556 | 3779 | 12820 |
| Sherman | city | Wyoming | United States | 41.09778 | -105.35028 | 7998 | 29 |
| Shirley historical | city | Wyoming | United States | 42.18889 | -106.48139 | 7230 | 5 |
| Shoshoni | city | Wyoming | United States | 43.23583 | -108.10972 | 4806 | 36 |
| Sibylee | city | Wyoming | United States | 42.08139 | -104.94972 | 4678 | 2823 |
| Silver Tip | city | Wyoming | United States | 41.91472 | -104.26611 | 4199 | 162 |
| Sinclair | city | Wyoming | United States | 41.775 | -107.1125 | 6604 | 33 |
| Skull Creek | city | Wyoming | United States | 44.10917 | -104.36667 | 4977 | 42 |
| Slater | city | Wyoming | United States | 41.87306 | -104.81944 | 4999 | 47 |
| Sleepy Hollow | city | Wyoming | United States | 44.24111 | -105.42167 | 4599 | 4101 |
| Smoot | city | Wyoming | United States | 42.62056 | -110.91361 | 6738 | 774 |
| Snyder Place | city | Wyoming | United States | 43.41917 | -107.55722 | 6220 | 25 |
| Soda Butte historical | city | Wyoming | United States | 44.87778 | -110.1525 | 6824 | 42 |
| South Baxter | city | Wyoming | United States | 41.36806 | -109.12111 | 7326 | 0 |
| South Flat | city | Wyoming | United States | 43.92972 | -108.00306 | 4196 | 597 |
| South Greeley | city | Wyoming | United States | 41.09694 | -104.80583 | 6056 | 35795 |
| South Park | city | Wyoming | United States | 43.42222 | -110.7925 | 6115 | 3687 |
| South Pass City | city | Wyoming | United States | 42.46833 | -108.79917 | 7818 | 42 |
| South Superior | city | Wyoming | United States | 41.76194 | -108.96611 | 6968 | 19 |
| South Torrington | city | Wyoming | United States | 42.04972 | -104.17889 | 4097 | 4105 |
| Speer | city | Wyoming | United States | 41.05444 | -104.895 | 6289 | 1122 |
| Spotted Horse | city | Wyoming | United States | 44.70833 | -105.83444 | 4009 | 33 |
| Squaw Hollow historical | city | Wyoming | United States | 41.16361 | -109.55972 | 6040 | 4 |
| Squaw Place | city | Wyoming | United States | 42.37 | -105.70333 | 7693 | 5 |
| Stansbury | city | Wyoming | United States | 41.70278 | -109.18722 | 6735 | 4622 |
| Story | city | Wyoming | United States | 44.57472 | -106.88611 | 4963 | 294 |
| Stroner | city | Wyoming | United States | 44.76667 | -105.045 | 3999 | 45 |
| Strouds | city | Wyoming | United States | 42.855 | -106.24083 | 5170 | 10019 |
| Sundance | city | Wyoming | United States | 44.40639 | -104.37528 | 4799 | 106 |
| Sunrise | city | Wyoming | United States | 42.33028 | -104.705 | 4999 | 116 |
| Sunshine | city | Wyoming | United States | 44.0275 | -108.99028 | 6558 | 28 |
| Superior | city | Wyoming | United States | 41.76944 | -108.97583 | 7001 | 19 |
| Sussex | city | Wyoming | United States | 43.69833 | -106.29444 | 4386 | 5 |
| Sussex Unit | city | Wyoming | United States | 43.60778 | -106.20139 | 4999 | 11 |
| Swaim Place | city | Wyoming | United States | 43.34806 | -107.37556 | 7201 | 5 |
| Sweeney Ranch | city | Wyoming | United States | 41.47972 | -109.01056 | 6748 | 0 |
| Sweetwater Crossing | city | Wyoming | United States | 42.54167 | -108.17889 | 6650 | 8 |
| Sweetwater Station | city | Wyoming | United States | 42.54222 | -108.18306 | 6597 | 8 |
| Sylvan Bay Summer Home Area | city | Wyoming | United States | 42.95444 | -109.78444 | 7716 | 33 |
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