| Name | What | Region | Country | Lat | Long | Elev Ft. | Pop Est |
|---|
| Yacht Club Estates | city | South Carolina | United States | 32.40583 | -80.66611 | 9 | 16299 |
| Yacht Cove | city | South Carolina | United States | 34.07083 | -81.2325 | 370 | 28321 |
| Yale historical | city | South Carolina | United States | 33.28111 | -81.33306 | 219 | 4525 |
| Yarborough Crossroads | city | South Carolina | United States | 34.24417 | -80.02139 | 170 | 3102 |
| Yauhannah | city | South Carolina | United States | 33.63194 | -79.18861 | 26 | 1062 |
| Yaupon Circle subdivision | city | South Carolina | United States | 33.68139 | -78.89361 | 0 | 25853 |
| Yellow House Landing | city | South Carolina | United States | 32.90833 | -79.925 | 22 | 30751 |
| Yellow House historical | city | South Carolina | United States | 32.8925 | -79.925 | 9 | 30751 |
| Yemassee | city | South Carolina | United States | 32.69 | -80.85083 | 19 | 1450 |
| Yenome | city | South Carolina | United States | 33.18333 | -81.34694 | 200 | 1778 |
| Yonges Island | city | South Carolina | United States | 32.69333 | -80.23083 | 3 | 3777 |
| York | city | South Carolina | United States | 34.99417 | -81.24222 | 702 | 10795 |
| York Hills subdivision | city | South Carolina | United States | 35.04028 | -81.65417 | 731 | 8467 |
| York Terrace | city | South Carolina | United States | 34.72167 | -81.20722 | 557 | 11187 |
| Yorkdale | city | South Carolina | United States | 34.90639 | -80.92917 | 666 | 10425 |
| Yorkshire subdivision | city | South Carolina | United States | 33.98222 | -80.94194 | 278 | 51667 |
| Yorkwood | city | South Carolina | United States | 34.80417 | -82.54667 | 961 | 23921 |
| Youngs | city | South Carolina | United States | 34.67056 | -82.08083 | 705 | 6931 |
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