| Name | What | Region | Country | Lat | Long | Elev Ft. | Pop Est |
|---|
| Sibleyville | city | Pennsylvania | United States | 41.98361 | -80.04694 | 1236 | 5690 |
| Sickler Hill | city | Pennsylvania | United States | 41.2275 | -75.97694 | 600 | 35748 |
| Sickles Corner | city | Pennsylvania | United States | 40.55389 | -78.28306 | 1256 | 5526 |
| Siddonsburg | city | Pennsylvania | United States | 40.14583 | -76.96639 | 698 | 23270 |
| Sidley | city | Pennsylvania | United States | 40.06556 | -75.56278 | 351 | 31820 |
| Sidman | city | Pennsylvania | United States | 40.33056 | -78.745 | 1728 | 6828 |
| Sidney | city | Pennsylvania | United States | 40.87722 | -78.80944 | 1683 | 1752 |
| Sigel | city | Pennsylvania | United States | 41.275 | -79.11333 | 1794 | 1527 |
| Siglerville | city | Pennsylvania | United States | 40.73944 | -77.53278 | 793 | 2509 |
| Sigmund | city | Pennsylvania | United States | 40.47333 | -75.55917 | 600 | 20251 |
| Sigsbee | city | Pennsylvania | United States | 39.82778 | -79.95639 | 898 | 7254 |
| Siko | city | Pennsylvania | United States | 41.67389 | -75.25361 | 1400 | 1502 |
| Siles | city | Pennsylvania | United States | 40.15556 | -74.97111 | 200 | 138778 |
| Silkworth | city | Pennsylvania | United States | 41.27222 | -76.08667 | 1197 | 4463 |
| Silvara | city | Pennsylvania | United States | 41.69861 | -76.13472 | 938 | 2115 |
| Silver Creek | city | Pennsylvania | United States | 40.73278 | -76.13361 | 882 | 17316 |
| Silver Ford Heights | city | Pennsylvania | United States | 40.37722 | -77.84861 | 600 | 5468 |
| Silver Mills | city | Pennsylvania | United States | 39.75639 | -78.36417 | 810 | 1098 |
| Silver Spring | city | Pennsylvania | United States | 40.06417 | -76.4375 | 475 | 35477 |
| Silver Spring | city | Pennsylvania | United States | 41.29944 | -74.84917 | 744 | 4618 |
| Silverdale | city | Pennsylvania | United States | 40.3475 | -75.27139 | 465 | 35506 |
| Silverton | city | Pennsylvania | United States | 40.65861 | -76.27083 | 1197 | 14536 |
| Silverville | city | Pennsylvania | United States | 40.70444 | -79.72306 | 1056 | 16314 |
| Simmonstown | city | Pennsylvania | United States | 39.97556 | -75.99417 | 597 | 11924 |
| Simpson | city | Pennsylvania | United States | 41.83667 | -78.58833 | 2194 | 2103 |
| Simpson | city | Pennsylvania | United States | 41.59167 | -75.48556 | 1322 | 13459 |
| Simpson Store | city | Pennsylvania | United States | 39.97833 | -80.39833 | 1341 | 2153 |
| Singersville | city | Pennsylvania | United States | 40.37722 | -76.91194 | 938 | 5703 |
| Sinking Spring | city | Pennsylvania | United States | 40.32722 | -76.01139 | 354 | 42585 |
| Sinnemahoning | city | Pennsylvania | United States | 41.31917 | -78.09667 | 1574 | 371 |
| Sinsheim | city | Pennsylvania | United States | 39.80472 | -76.86639 | 613 | 8433 |
| Siousca | city | Pennsylvania | United States | 40.00417 | -75.82111 | 396 | 35793 |
| Sipes Mill | city | Pennsylvania | United States | 39.91056 | -78.15278 | 800 | 1237 |
| Sipesville | city | Pennsylvania | United States | 40.09917 | -79.09139 | 2096 | 3428 |
| Sistersville | city | Pennsylvania | United States | 40.78611 | -79.6125 | 1286 | 5451 |
| Sitka | city | Pennsylvania | United States | 39.99139 | -79.61167 | 997 | 17466 |
| Siverly | city | Pennsylvania | United States | 41.42056 | -79.69361 | 997 | 14528 |
| Six Points | city | Pennsylvania | United States | 41.14056 | -79.755 | 1496 | 2364 |
| Sizerville | city | Pennsylvania | United States | 41.58861 | -78.19806 | 1197 | 511 |
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