| Name | What | Region | Country | Lat | Long | Elev Ft. | Pop Est |
|---|
| Sagwon | city | Alaska | United States | 69.37306 | -148.70056 | 734 | 0 |
| Saint George | city | Alaska | United States | 56.6 | -169.54167 | 242 | 0 |
| Saint John Harbor | city | Alaska | United States | 56.43972 | -132.96361 | 0 | 14 |
| Saint Marys | city | Alaska | United States | 62.05306 | -163.16583 | 3 | 5 |
| Saint Michael | city | Alaska | United States | 63.47806 | -162.03917 | 0 | 1 |
| Saint Paul | city | Alaska | United States | 57.12222 | -170.275 | 32 | 0 |
| Saint Terese | city | Alaska | United States | 58.47222 | -134.78028 | 298 | 79 |
| Salt Chuck | city | Alaska | United States | 55.62639 | -132.55361 | 82 | 46 |
| Sanak | city | Alaska | United States | 54.47806 | -162.8175 | 65 | 0 |
| Sand Point | city | Alaska | United States | 55.33972 | -160.49722 | 68 | 3 |
| Savonoski | city | Alaska | United States | 58.71722 | -156.86389 | 29 | 70 |
| Savoonga | city | Alaska | United States | 63.69417 | -170.47889 | 108 | 2 |
| Saxman | city | Alaska | United States | 55.31833 | -131.59583 | 0 | 3637 |
| Scammon Bay | city | Alaska | United States | 61.84278 | -165.58167 | 498 | 5 |
| Scow Bay | city | Alaska | United States | 56.77028 | -132.96028 | 311 | 893 |
| Selawik | city | Alaska | United States | 66.60389 | -160.00694 | 3 | 5 |
| Seldovia | city | Alaska | United States | 59.43806 | -151.71139 | 137 | 65 |
| Seldovia Village | city | Alaska | United States | 59.47806 | -151.65194 | 203 | 60 |
| Serpentine Hot Springs | city | Alaska | United States | 65.85694 | -164.71417 | 577 | 5 |
| Seversens | city | Alaska | United States | 59.75361 | -154.81722 | 45 | 0 |
| Seward | city | Alaska | United States | 60.10417 | -149.44222 | 52 | 937 |
| Shageluk | city | Alaska | United States | 62.68222 | -159.56194 | 62 | 0 |
| Shaktoolik | city | Alaska | United States | 64.33389 | -161.15389 | 6 | 4 |
| Sheshalik | city | Alaska | United States | 66.99417 | -162.82806 | 0 | 0 |
| Shirleyville | city | Alaska | United States | 61.01361 | -151.40694 | 0 | 0 |
| Shishmaref | city | Alaska | United States | 66.25667 | -166.07194 | 3 | 1 |
| Shoreline Drive | city | Alaska | United States | 55.375 | -131.725 | 0 | 5098 |
| Shungnak | city | Alaska | United States | 66.88806 | -157.13639 | 98 | 5 |
| Silvertip | city | Alaska | United States | 60.75056 | -149.36972 | 531 | 19 |
| Sinuk | city | Alaska | United States | 64.59278 | -166.25278 | 0 | 9 |
| Sitka | city | Alaska | United States | 57.05306 | -135.33 | 0 | 5688 |
| Situk | city | Alaska | United States | 59.43528 | -139.55472 | 0 | 3 |
| Skagway | city | Alaska | United States | 59.45833 | -135.31389 | 557 | 45 |
| Skwentna | city | Alaska | United States | 61.99028 | -151.39778 | 137 | 0 |
| Slaterville | city | Alaska | United States | 64.84806 | -147.72361 | 433 | 24078 |
| Sleetmute | city | Alaska | United States | 61.7025 | -157.16972 | 187 | 0 |
| Snug Harbor | city | Alaska | United States | 60.48917 | -149.78417 | 501 | 19 |
| Soldotna | city | Alaska | United States | 60.48778 | -151.05833 | 85 | 4279 |
| Solomon | city | Alaska | United States | 64.56083 | -164.43917 | 9 | 4 |
| South Fairbanks | city | Alaska | United States | 64.83333 | -147.71667 | 433 | 18705 |
| South Naknek | city | Alaska | United States | 58.71556 | -156.99806 | 98 | 67 |
| Spenard | city | Alaska | United States | 61.18861 | -149.90639 | 95 | 81320 |
| Squaw Harbor | city | Alaska | United States | 55.24333 | -160.55333 | 0 | 5 |
| Standard | city | Alaska | United States | 64.78083 | -148.52972 | 383 | 61 |
| Starr Hill | city | Alaska | United States | 58.30417 | -134.40417 | 797 | 2085 |
| Stebbins | city | Alaska | United States | 63.52222 | -162.28806 | 36 | 3 |
| Sterling | city | Alaska | United States | 60.53722 | -150.76472 | 183 | 504 |
| Stevens Village | city | Alaska | United States | 66.00639 | -149.09083 | 301 | 0 |
| Stony River | city | Alaska | United States | 61.78306 | -156.58806 | 219 | 0 |
| Strelna | city | Alaska | United States | 61.51139 | -144.06889 | 1286 | 0 |
| Stuyahok | city | Alaska | United States | 62.06028 | -160.95083 | 498 | 4 |
| Sulatna Crossing | city | Alaska | United States | 64.18917 | -155.46361 | 344 | 0 |
| Sullivan Camp | city | Alaska | United States | 65.06306 | -166.19528 | 370 | 5 |
| Summit | city | Alaska | United States | 63.33139 | -149.12222 | 2316 | 1 |
| Sunnyside | city | Alaska | United States | 57.98278 | -136.25222 | 0 | 5 |
| Sunrise | city | Alaska | United States | 60.88667 | -149.42778 | 196 | 13 |
| Sunshine | city | Alaska | United States | 62.16778 | -150.07306 | 347 | 75 |
| Suntrana | city | Alaska | United States | 63.85417 | -148.84833 | 1597 | 5 |
| Susitna | city | Alaska | United States | 61.54361 | -150.5125 | 88 | 0 |
| Sutton | city | Alaska | United States | 61.71139 | -148.89417 | 682 | 61 |
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