| Name | What | Region | Country | Lat | Long | Elev Ft. | Pop Est |
| Scalesville | city | Indiana | United States | 38.2025 | -87.20611 | 498 | 1404 |
| Scarlet | city | Indiana | United States | 38.65778 | -86.6675 | 751 | 1353 |
| Scarlet Oaks | city | Indiana | United States | 40.69556 | -86.75417 | 606 | 6694 |
| Scenic Hill | city | Indiana | United States | 38.67833 | -86.89389 | 449 | 4651 |
| Schererville | city | Indiana | United States | 41.47889 | -87.45472 | 652 | 54011 |
| Schley | city | Indiana | United States | 38.04556 | -86.87194 | 400 | 1882 |
| Schneider | city | Indiana | United States | 41.18694 | -87.44833 | 629 | 3458 |
| Schnellville | city | Indiana | United States | 38.34111 | -86.75611 | 600 | 1856 |
| Schooler Point Landing | city | Indiana | United States | 38.15806 | -86.34139 | 495 | 1226 |
| Scipio | city | Indiana | United States | 39.07917 | -85.7175 | 695 | 3687 |
| Scipio | city | Indiana | United States | 39.39194 | -84.81833 | 892 | 3510 |
| Scircleville | city | Indiana | United States | 40.2875 | -86.3 | 915 | 1449 |
| Scotchtown | city | Indiana | United States | 39.075 | -87.29778 | 498 | 1488 |
| Scotland | city | Indiana | United States | 38.91278 | -86.90389 | 649 | 1288 |
| Scott | city | Indiana | United States | 41.73361 | -85.55694 | 807 | 4303 |
| Scott City | city | Indiana | United States | 39.19389 | -87.465 | 518 | 1341 |
| Scott Corner | city | Indiana | United States | 40.09194 | -85.12694 | 1148 | 1975 |
| Scottsburg | city | Indiana | United States | 38.28861 | -87.21917 | 449 | 1679 |
| Scottsburg | city | Indiana | United States | 38.68556 | -85.77028 | 564 | 9320 |
| Scottsville | city | Indiana | United States | 38.40194 | -85.90917 | 895 | 7110 |
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