| Name | What | Region | Country | Lat | Long | Elev Ft. | Pop Est |
|---|
| Escombe | city | Province of KwaZulu-Natal | South Africa | -29.8666667 | 30.9 | 236 | 178175 |
| Esehlabeni | city | | South Africa | -30.1666667 | 28.9166667 | 5462 | 10288 |
| Eselfontein | city | | South Africa | -33.4 | 19.4333333 | 1627 | 687 |
| Eseljag | city | | South Africa | -33.8 | 22.5666667 | 1833 | 5656 |
| Eshowe | city | Province of KwaZulu-Natal | South Africa | -28.8833333 | 31.4666667 | 1774 | 9177 |
| Esibhoweni | city | Province of KwaZulu-Natal | South Africa | -27.3666667 | 32.4166667 | 226 | 5478 |
| Esibudeni | city | Province of KwaZulu-Natal | South Africa | -28.75 | 31.1666667 | 3782 | 9348 |
| Esibudeni Store | city | Province of KwaZulu-Natal | South Africa | -28.75 | 31.1666667 | 3782 | 9348 |
| Esibudeni Store Site | city | Province of KwaZulu-Natal | South Africa | -28.75 | 31.1666667 | 3782 | 9348 |
| Esikhawini Township | city | Province of KwaZulu-Natal | South Africa | -28.8833333 | 31.9 | 131 | 18080 |
| Esikhobeni | city | | South Africa | -32.4166667 | 28.2333333 | 1866 | 11397 |
| Esikobeni | city | | South Africa | -32.0166667 | 28.0833333 | 2673 | 8788 |
| Esinquineni | city | | South Africa | -32.0166667 | 28.25 | 2769 | 9204 |
| Esinxago | city | | South Africa | -31.1 | 28.6 | 2887 | 8898 |
| Esitangameni | city | | South Africa | -31.0333333 | 28.8 | 3543 | 10120 |
| Eskdale | city | | South Africa | -26.7833333 | 23.7 | 3877 | 1142 |
| Eskdale | city | | South Africa | -26.7833333 | 23.7166667 | 3828 | 1138 |
| Eskweleni | city | | South Africa | -31.8 | 28.9 | 987 | 11392 |
| Esperanza | city | | South Africa | -27.25 | 23.4666667 | 4068 | 1772 |
| Esperanza | city | | South Africa | -31.5666667 | 26.65 | 5026 | 504 |
| Esperanza | city | Province of KwaZulu-Natal | South Africa | -30.3333333 | 30.65 | 160 | 9442 |
| Esseldene | city | Province of KwaZulu-Natal | South Africa | -29.5333333 | 30.05 | 4314 | 3266 |
| Essenwood | city | Province of KwaZulu-Natal | South Africa | -29.8333333 | 31.0166667 | 164 | 139690 |
| Estancia | city | | South Africa | -26.3333333 | 29.8666667 | 5964 | 1750 |
| Estcourt | city | Province of KwaZulu-Natal | South Africa | -29 | 29.8833333 | 3927 | 1979 |
| Eswana | city | | South Africa | -30.9333333 | 29.65 | 2499 | 12416 |
| Eswane | city | | South Africa | -30.9333333 | 29.65 | 2499 | 12416 |