| Name | What | Region | Country | Lat | Long | Elev ft. | Pop est |
|---|---|---|---|---|---|---|---|
| Salinas Santa Rosa | city | Escuintla | Guatemala | 13.93 | -90.82 | 16 | 18494 |
| Salto | city | Escuintla | Guatemala | 14.30 | -90.75 | 885 | 56487 |
| San Andrés | city | Escuintla | Guatemala | 14.38 | -90.92 | 2601 | 5925 |
| San Antonio | city | Escuintla | Guatemala | 14.30 | -90.95 | 964 | 12492 |
| San Antonio | city | Escuintla | Guatemala | 14.10 | -91.12 | 118 | 8493 |
| San Francisco | city | Escuintla | Guatemala | 14.23 | -90.67 | 980 | 5426 |
| San Francisco Madre Vieja | city | Escuintla | Guatemala | 14.03 | -91.45 | 16 | 8044 |
| San Francisco Verapaz | city | Escuintla | Guatemala | 14.23 | -90.67 | 980 | 5426 |
| San Francisco de Sales | city | Escuintla | Guatemala | 14.42 | -90.60 | 5967 | 75443 |
| San Isidro Boton Blanco | city | Escuintla | Guatemala | 14.00 | -90.91 | 78 | 10217 |
| San Jeronimo | city | Escuintla | Guatemala | 14.03 | -91.10 | 75 | 8485 |
| San Jose Bejucal | city | Escuintla | Guatemala | 14.42 | -90.60 | 5967 | 75443 |
| San Jose Rama Blanca | city | Escuintla | Guatemala | 13.93 | -91.23 | 0 | 4031 |
| San José | city | Escuintla | Guatemala | 13.92 | -90.82 | 0 | 16865 |
| San José | city | Escuintla | Guatemala | 13.93 | -90.82 | 16 | 18494 |
| San José | city | Escuintla | Guatemala | 14.35 | -91.10 | 974 | 23997 |
| San José Mogollón | city | Escuintla | Guatemala | 14.20 | -91.25 | 193 | 15784 |
| San José de Guatemala | city | Escuintla | Guatemala | 13.93 | -90.82 | 16 | 18494 |
| San Juan | city | Escuintla | Guatemala | 14.22 | -90.70 | 830 | 6524 |
| San Juan Mixtán | city | Escuintla | Guatemala | 14.22 | -90.83 | 830 | 35086 |
| San Luis | city | Escuintla | Guatemala | 14.30 | -90.80 | 1020 | 96513 |
| San Nicolás Hacienda Nueva | city | Escuintla | Guatemala | 14.23 | -90.80 | 830 | 42157 |
| San Pedro Nahualate | city | Escuintla | Guatemala | 14.05 | -91.53 | 3 | 8101 |
| San Raimundo | city | Escuintla | Guatemala | 14.38 | -90.75 | 2696 | 33713 |
| San Vicente | city | Escuintla | Guatemala | 14.42 | -90.64 | 5190 | 78455 |
| San Vicente Mártir | city | Escuintla | Guatemala | 14.42 | -90.64 | 5190 | 78455 |
| San Vicente Pacaya | city | Escuintla | Guatemala | 14.42 | -90.64 | 5190 | 78455 |
| Santa Ana Mixtan | city | Escuintla | Guatemala | 14.12 | -91.23 | 111 | 17597 |
| Santa Anita | city | Escuintla | Guatemala | 14.10 | -90.58 | 144 | 6581 |
| Santa Isabel | city | Escuintla | Guatemala | 13.97 | -90.86 | 52 | 17610 |
| Santa Lucía | city | Escuintla | Guatemala | 14.33 | -91.02 | 1210 | 32564 |
| Santa Lucía Cotzumalguapa | city | Escuintla | Guatemala | 14.33 | -91.02 | 1210 | 32564 |
| Santa Marta | city | Escuintla | Guatemala | 13.97 | -91.30 | 16 | 12235 |
| Santa Marta el Mar | city | Escuintla | Guatemala | 13.97 | -91.30 | 16 | 12235 |
| Santa Rita | city | Escuintla | Guatemala | 14.13 | -90.97 | 190 | 6710 |
| Santa Rosa | city | Escuintla | Guatemala | 13.93 | -90.82 | 16 | 18494 |
| Santa Sofia | city | Escuintla | Guatemala | 14.38 | -90.98 | 1984 | 19383 |
| Santo Domingo | city | Escuintla | Guatemala | 14.20 | -90.70 | 334 | 5605 |
| Semillero | city | Escuintla | Guatemala | 14.05 | -91.52 | 6 | 8209 |
| Sipacate | city | Escuintla | Guatemala | 13.93 | -91.15 | 16 | 5061 |
| Siquinala | city | Escuintla | Guatemala | 14.31 | -90.97 | 1138 | 16790 |
| Suquite | city | Escuintla | Guatemala | 13.98 | -90.79 | 36 | 18620 |