| Name | What | Region | Country | Lat | Long | Elev ft. | Pop est |
|---|---|---|---|---|---|---|---|
| Escalera | city | Azuay | Ecuador | -3.52 | -79.18 | 9563 | 2257 |
| Escalera | city | Pichincha | Ecuador | 0.00 | -78.93 | 3349 | 2777 |
| Escaleras | city | Azuay | Ecuador | -3.52 | -79.18 | 9563 | 2257 |
| Escaleras | city | Azuay | Ecuador | -3.04 | -79.06 | 9228 | 6148 |
| Escalón | city | Manabi | Ecuador | -0.28 | -80.02 | 1000 | 3445 |
| Escudero | city | Tungurahua | Ecuador | -1.07 | -78.53 | 10068 | 21757 |
| Escudero | city | Pichincha | Ecuador | -0.55 | -78.60 | 10095 | 8359 |
| Esmeralda | city | Tungurahua | Ecuador | -1.22 | -78.48 | 10095 | 5678 |
| Esmeralda | city | Pichincha | Ecuador | -0.37 | -78.45 | 8805 | 59651 |
| Esmeraldas | city | Azuay | Ecuador | -3.33 | -79.40 | 3733 | 3554 |
| Esmeraldas | city | Guayas | Ecuador | -1.87 | -79.80 | 88 | 19405 |
| Esmeraldas | city | Esmeraldas | Ecuador | 0.97 | -79.65 | 3 | 87054 |
| Esmeraldas | city | Cotopaxi | Ecuador | -0.65 | -79.11 | 4402 | 2890 |
| Esmeraldas Libre | city | Sucumbios | Ecuador | 0.07 | -76.89 | 1669 | 23443 |
| Esmeraldita | city | Guayas | Ecuador | -2.31 | -80.18 | 360 | 29540 |
| Espana | city | Guayas | Ecuador | -1.87 | -79.77 | 85 | 17656 |
| Espejo | city | Imbabura | Ecuador | 0.21 | -78.24 | 8612 | 41610 |
| Espejo | city | Carchi | Ecuador | 0.62 | -77.94 | 10908 | 8070 |
| Esperanza | city | Manabi | Ecuador | -1.58 | -80.52 | 961 | 9417 |
| Esperanza | city | Los Rios | Ecuador | -1.52 | -79.48 | 987 | 14278 |
| Esperanza | city | Imbabura | Ecuador | 0.30 | -78.12 | 8405 | 50548 |
| Esperanza | city | Tungurahua | Ecuador | -1.07 | -78.53 | 10068 | 21757 |
| Esperanza | city | Pichincha | Ecuador | -0.30 | -78.40 | 8644 | 44301 |
| Esperanza | city | Guayas | Ecuador | -2.22 | -80.25 | 830 | 11879 |
| Esperanza | city | Los Rios | Ecuador | -1.95 | -79.37 | 830 | 7076 |
| Esperanza | city | Guayas | Ecuador | -1.87 | -79.77 | 85 | 17656 |
| Esperanza | city | Los Rios | Ecuador | -1.53 | -79.78 | 144 | 24564 |
| Espinal | city | Guayas | Ecuador | -2.67 | -80.05 | 0 | 673 |
| Espinel | city | Tungurahua | Ecuador | -1.17 | -78.52 | 10190 | 23999 |
| Espiritu | city | Loja | Ecuador | -4.05 | -79.78 | 3349 | 2783 |
| Estacada | city | Guayas | Ecuador | -2.00 | -79.97 | 52 | 228648 |
| Estacada | city | Guayas | Ecuador | -1.82 | -80.26 | 341 | 19166 |
| Estacion Cumbe | city | Azuay | Ecuador | -3.04 | -79.05 | 9228 | 6148 |
| Estación de Cumbe | city | Azuay | Ecuador | -3.04 | -79.05 | 9228 | 6148 |
| Estancada | city | Guayas | Ecuador | -1.82 | -80.26 | 341 | 19166 |
| Estancia | city | Manabi | Ecuador | -1.14 | -80.40 | 282 | 42796 |
| Estancia Vieja | city | Guayas | Ecuador | -2.07 | -79.88 | 26 | 144146 |
| Estancias Viejas | city | Manabi | Ecuador | -1.14 | -80.40 | 282 | 42796 |
| Estancilla | city | Manabi | Ecuador | -0.82 | -80.22 | 272 | 12021 |
| Estela | city | Cotopaxi | Ecuador | -0.75 | -78.88 | 9481 | 2207 |
| Estela | city | Pichincha | Ecuador | -0.30 | -78.47 | 8389 | 194908 |
| Estero | city | Guayas | Ecuador | -2.26 | -79.87 | 3 | 94010 |
| Estero Chico de Arriba | city | Guayas | Ecuador | -0.88 | -79.58 | 344 | 3172 |
| Estero Cobina | city | Guayas | Ecuador | -2.26 | -79.87 | 3 | 94010 |
| Estero Frio | city | Santo Domingo de los Tsachilas | Ecuador | -0.37 | -79.16 | 2509 | 11703 |
| Estero Lagarto | city | Guayas | Ecuador | -1.73 | -79.92 | 98 | 18735 |
| Estero de Boca | city | Guayas | Ecuador | -2.79 | -80.23 | 26 | 786 |
| Estrella | city | Guayas | Ecuador | -1.83 | -79.80 | 95 | 23138 |
| Estrella Yacu | city | Orellana | Ecuador | -0.43 | -77.12 | 984 | 12 |
| Estrella del Oriente | city | Sucumbios | Ecuador | 0.07 | -76.88 | 1669 | 25125 |
| Estupiñán | city | Cotopaxi | Ecuador | -1.00 | -78.62 | 9228 | 34066 |