| Name | What | Region | Country | Lat | Long | Elev ft. | Pop est |
|---|---|---|---|---|---|---|---|
| San Andrés | city | Putumayo | Colombia | 1.13 | -76.99 | 7549 | 6442 |
| San Antonio | city | Putumayo | Colombia | 0.47 | -76.91 | 1899 | 4155 |
| San Antonio | city | Putumayo | Colombia | 1.18 | -76.68 | 3467 | 11265 |
| San Antonio del Guamues | city | Putumayo | Colombia | 0.57 | -76.83 | 1866 | 2682 |
| San Diego Viejo | city | Putumayo | Colombia | 0.62 | -76.58 | 1669 | 1372 |
| San Francisco | city | Putumayo | Colombia | 0.33 | -75.00 | 830 | 40 |
| San Francisco | city | Putumayo | Colombia | 1.18 | -76.88 | 7122 | 3662 |
| San Joaquin | city | Putumayo | Colombia | 1.32 | -76.58 | 3349 | 753 |
| San Jose | city | Putumayo | Colombia | 0.88 | -76.41 | 1669 | 933 |
| San Jose | city | Putumayo | Colombia | 0.55 | -76.47 | 1669 | 16237 |
| San Luis | city | Putumayo | Colombia | 0.66 | -76.47 | 1669 | 1341 |
| San Luis | city | Putumayo | Colombia | 0.88 | -76.58 | 1778 | 3152 |
| San Luis de Chontayaco | city | Putumayo | Colombia | 1.15 | -76.68 | 3349 | 11405 |
| San Marcelino | city | Putumayo | Colombia | 0.27 | -76.83 | 1669 | 880 |
| San Miguel | city | Putumayo | Colombia | 0.34 | -76.91 | 1669 | 5568 |
| San Miguel | city | Putumayo | Colombia | 0.13 | -75.85 | 830 | 132 |
| San Miguel Nuevo | city | Putumayo | Colombia | 0.34 | -76.91 | 1669 | 5568 |
| San Pedro | city | Putumayo | Colombia | 0.63 | -76.58 | 1669 | 1343 |
| San Roque | city | Putumayo | Colombia | 1.03 | -75.99 | 1669 | 2468 |
| Santa Ana | city | Putumayo | Colombia | 0.60 | -76.57 | 1669 | 1451 |
| Santa Barbara | city | Putumayo | Colombia | -0.14 | -74.43 | 406 | 60 |
| Santa Lucia | city | Putumayo | Colombia | 1.01 | -77.18 | 10068 | 8791 |
| Santa Lucia | city | Putumayo | Colombia | 0.96 | -76.44 | 1712 | 756 |
| Santa Maria | city | Putumayo | Colombia | 0.47 | -76.54 | 1669 | 13494 |
| Santa Rosa | city | Putumayo | Colombia | 0.73 | -76.59 | 1669 | 1362 |
| Santa Rosa | city | Putumayo | Colombia | 1.04 | -75.96 | 1230 | 3001 |
| Santa Rosa de Los Estilleros | city | Putumayo | Colombia | 0.91 | -76.34 | 1669 | 877 |
| Santiago | city | Putumayo | Colombia | 1.15 | -77.00 | 7549 | 6424 |
| Sibundoy | city | Putumayo | Colombia | 1.20 | -76.92 | 7549 | 15122 |