UpAlphabetical listing of Places in Southern
| Name | What | Region | Country | Lat | Long | Elev ft. | Pop est |
| Seatlhodi | city | Southern | Botswana | -24.74 | 23.38 | 3490 | 447 |
| Sedibeng | city | Southern | Botswana | -25.60 | 25.16 | 4189 | 298 |
| Sefhetla | city | Southern | Botswana | -25.35 | 25.37 | 4189 | 298 |
| Segwagwa | city | Southern | Botswana | -25.18 | 25.17 | 4189 | 298 |
| Segwagwa | city | Southern | Botswana | -25.19 | 25.17 | 4189 | 298 |
| Sehikile | city | Southern | Botswana | -25.42 | 25.33 | 4202 | 456 |
| Sehubidu | city | Southern | Botswana | -24.73 | 25.28 | 4189 | 447 |
| Sekalaba | city | Southern | Botswana | -25.05 | 25.34 | 4245 | 2147 |
| Sekgwa | city | Southern | Botswana | -24.80 | 25.60 | 4189 | 391 |
| Sekgwasentsho | city | Southern | Botswana | -24.32 | 23.38 | 3556 | 447 |
| Sekhawawa | city | Southern | Botswana | -25.19 | 25.17 | 4189 | 298 |
| Sekhwawa | city | Southern | Botswana | -25.19 | 25.17 | 4189 | 298 |
| Sekoma | city | Southern | Botswana | -24.40 | 23.88 | 3585 | 1015 |
| Sekoma | city | Southern | Botswana | -24.52 | 23.93 | 3523 | 447 |
| Selokolela | city | Southern | Botswana | -24.95 | 25.11 | 4189 | 401 |
| Senokwane | city | Southern | Botswana | -24.77 | 25.02 | 4222 | 447 |
| Sentsi | city | Southern | Botswana | -24.74 | 25.33 | 4189 | 3949 |
| Seokangwane | city | Southern | Botswana | -25.28 | 25.39 | 4189 | 298 |
| Seokangwane | city | Southern | Botswana | -24.81 | 25.54 | 4189 | 832 |
| Seokopi | city | Southern | Botswana | -24.68 | 23.72 | 3444 | 447 |
| Sephatlhaphatla | city | Southern | Botswana | -24.72 | 25.46 | 3520 | 4852 |
| Seretologane | city | Southern | Botswana | -24.83 | 25.56 | 4235 | 447 |
| Serowe | city | Southern | Botswana | -24.84 | 25.57 | 4189 | 447 |
| Serumolwe | city | Southern | Botswana | -24.02 | 23.09 | 3661 | 262 |
| Sesitajwe | city | Southern | Botswana | -24.76 | 25.52 | 4189 | 12055 |
| Sesung | city | Southern | Botswana | -24.90 | 25.02 | 4189 | 301 |
| Sesunyane | city | Southern | Botswana | -24.80 | 25.35 | 3743 | 13616 |
| Setswamotlhabe | city | Southern | Botswana | -24.83 | 25.53 | 4189 | 447 |
| Silokwalela | city | Southern | Botswana | -24.95 | 25.11 | 4189 | 401 |
| Sistajwe | city | Southern | Botswana | -24.76 | 25.52 | 4189 | 12055 |
| Sobathwe | city | Southern | Botswana | -25.04 | 25.25 | 4412 | 424 |
| Sobe | city | Southern | Botswana | -24.85 | 25.46 | 4189 | 984 |
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